Effect of PKC on Retinal Oxygenation Response in Experimental Diabetes
نویسندگان
چکیده
METHODS. Retinal oxygenation response ( PO2) was measured using functional magnetic resonance imaging (MRI) and either carbogen or 100% oxygen inhalation challenge in C57BL/6J control (C) mice. Retinal PO2 during carbogen breathing was also measured in PKC knockout (C57BL6-Prkcb1; [KO]), 4 month C57BL/6J diabetic (D), and 4-month diabetic PKC KO (D KO) mice. Retinal PKC protein expression was assessed by Western analysis.
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تاریخ انتشار 2004